Our overarching goal is to unravel the role of the ubiquitin-26S proteasome system in plants.

Our lab studies how protein ubiquitylation regulates plant development, growth, and environmental responses. Taking advantage of high-throughput sequencing technologies, we investigate these processes in Arabidopsis thaliana and rice through the integration of evolutionary and computational biology, omics, genetics, biochemistry, and molecular biology. Our long-term goal is to develop new strategies for improving crop production through predictable manipulation of the ubiquitin–26S proteasome system.

Recent updates: The Hua Lab welcomes motivated Ph.D. applicants interested in plant protein ubiquitylation, proteostasis, autophagy, chloroplast signaling, genomics, and synthetic biology. Recent research highlights include UPS engineering, autophagy–proteasome crosstalk, MORF2-mediated chloroplast signaling, and nanopore-based RNA-editing analysis.